Laboratory Services

Biochemistry also called as biological chemistry (living things). Biochemistry is a branch of science concerned with the chemical and physico-chemical processes that occurs within living organisms. Biochemistry is the study of chemical processes within and relating to living organisms in the blood by controlling information flow through biochemical signaling and the flow of chemical energy through metabolism, biochemical processes give rise to the complexity of life. Biochemistry deals with the chemical compounds and processes occurring in organisms and the chemical characteristics and reactions of a particular living organism or biological substance.

IMMUNOASSAY

At our Advanced Laboratory we measures the presence or concentration of a macromolecule or a small molecule in a solution through the use of an antibody (usually) or an antigen (sometimes). The molecule detected by the immunoassay is often referred to as an “analyte” and is in many cases a protein, although it may be other kinds of molecules, of different size and types, as long as the proper antibodies that have the adequate properties for the assay are developed. Analytes in biological liquids such as serum are frequently measured using immunoassays for medical and research purposes

Chemistry

At Quadra, we follow the main principle of dry chemistry which is based upon the reflectance spectrophotometry.

Reflectance spectrophotometry measures the reflectance of materials. Reflectance measurements are of great value in providing a reference standard for the comparison of the colour of different samples.

Haematology

At our Automated Laboratory this branch of investigation is concerned with the study, diagnosis, treatment, and prevention of diseases related to blood. Hematology includes the study of etiology. It involves treating diseases that affect the production of blood and its components, such as blood cells, haemoglobin, blood proteins, bone marrow, platelets, blood vessels, spleen, and the mechanism of coagulation. Such diseases might include haemophilia, blood clots, other bleeding disorders and blood cancers such as leukemia, myeloma, and lymphoma.

At Quadra Immunohematology is performed using advanced flowcytometry technique which studies antigen–antibody reactions and analogous phenomena as they relate to the pathogenesis and clinical manifestations of blood disorders.

Clinical pathology

Quadra undertakes diagnosis of disease using laboratory testing of blood/urine/stool and other bodily fluids, tissues, and microscopic evaluation of individual cells. Our board-certified veterinary clinical pathologists and technologists provide laboratory results in a timely, efficient and thoughtful manner; supporting research, clinicians, referring veterinarians, and students in the diagnosis and treatment of many animal species.

At Quadra, Immunology covers the study of immune systems in all organisms. We chart, measure and contextualize the physiological functioning of the immune system in states of both health and diseases; malfunctions of the immune system in immunological disorders (such as autoimmune diseases, hypersensitivities, immune deficiency, and transplant rejection); the physical, chemical and physiological characteristics of the components of the immune system in vitro, in situ, and in vivo. Immunology is practiced in numerous disciplines at our lab, particularly in the fields of organ transplantation, oncology, virology, bacteriology, parasitology and dermatology.

At Quadra we perform microscopic examination of tissue in order to study the manifestations of disease. Specifically, in clinical medicine, histopathology refers to the examination of a biopsy or surgical specimen by a pathologist, after the specimen has been processed and histological sections have been placed onto glass slides at our fully automated histopathology lab.

In Immunohistochemistry section of our Laboratory tests are performed using antibodies to test for certain antigens (markers) in a sample of tissue. The antibodies are usually linked to an enzyme or a fluorescent dye. When the antibodies bind to the antigen in the tissue sample, the enzyme or dye is activated, and the antigen can then be seen under a microscope. Immunohistochemistry is used to help diagnose diseases, such as cancer. It may also be used to help tell the difference between different types of cancer.

Cytology is the study of cells. Cytology is that branch of life science that deals with the study of cells in terms of structure, function and chemistry.

• Real Time PCR Test is Highly Specific and Sensitive test
• tuberculosis is a very slow growing and fastidious bacteria
• For fast and accurate diagnosis TB PCR is an ideal choice of diagnosis
• Genexpert is also a form of Real Time PCR which not only detects Tuberculosis but also gives an indication of
• Rifampicin resistance. The reports are provided next day.
• HBV and HCV Viral load monitoring is essential for management of chronically infected hepatitis (B & C) patients.

• Automated Blood and body fluid culture is done by Bact/Alert system
• Automated identification and sensitivity (MIC) is provided by Vitek 2 System.
• Culture of Anaerobic organism are performed in the microbiology lab.
• Various Fungal stains (KOH Wet mount, PAS, India Ink) along with fungal culture is performed.
• Identification and sensitivity of yeast isolates are provided by Vitek 2 system Automated AFB CULTURE (BACTEC MGIT)

BACTEC MGIT (Mycobacterial Growth Indicator Tube) :

• Rapid, automated detection
• Susceptibility testing (1st line)
• Differentiation of mycobacterium (TB or MOTT)